Changes in version 2.0.4 (2024-08-21) - Fitted values and residuals have now the correct length even when there are zero weights. - Fixed a bug when calculating the variance for models with fixed parameters. - Function predict can now return standard errors and prediction intervals. - Upgraded Roxygen2 to version 7.3.2. Changes in version 2.0.3 (2023-03-17) - Updated vignette after review from the Journal of Statistical Software. - Fixed again the x-axis of the plot. Changes in version 2.0.2 (2022-11-25) - Fixed a bug in the plot when doses were not previously sorted. - Fixed a bug in the x-axis of the plot when data contained zeros. - It is now possible to not plot data points by setting option plot_data to FALSE (default TRUE). Changes in version 2.0.1 (2022-07-08) - Small fixes to unit tests because they were not passing on specific systems. - Updated vignette with new simulation results. Changes in version 2.0.0 (2022-06-17) It is now possible to fit models using either the log-dose or the dose scale. To accommodate this extension it was necessary to change the default model parameterization, which now follows that of the Emax model (Macdougall, 2006). Briefly, the 5-parameter logistic function is now defined as alpha + delta / (1 + nu * exp(-eta * (x - phi)))^(1 / nu) Parameter alpha is the value of the function when x approaches -Inf. Parameter delta is the (signed) height of the curve. Parameter eta > 0 represents the steepness (growth rate) of the curve. Parameter phi is related to the mid-value of the function. Parameter nu affects near which asymptote maximum growth occurs. Similarly, the newly implemented log-logistic function (when x >= 0) is defined as alpha + delta * (x^eta / (x^eta + nu * phi^eta))^(1 / nu) Check the vignette (vignette("drda", package = "drda")) or the help page (help(drda)) to know more about the available models. Here is a change log from previous version: - Change parameterization to follow that of the Emax model. - Implement the log-logistic family of models. - Improve initialization algorithm to be more efficient and (hopefully) robust. - Exported functions for evaluating theoretical gradient and Hessian of each implemented model. - Implement the effective_dose function for estimating effective doses. - Added examples to help pages. - Many minor bug fixes (too many to list them all). Changes in version 1.0.0 (2021-06-10) First public release.